Antiobesity and Antihyperglycemic Effects of Ginsenoside Rb1 in Rats

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Antiobesity and Antihyperglycemic Effects of Ginsenoside Rb1 in Rats

OBJECTIVE Obesity and type 2 diabetes are national and worldwide epidemics. Because currently available antiobesity and antidiabetic drugs have limited efficacy and/or safety concerns, identifying new medicinal agents, such as ginsenoside Rb1 (Rb1) as reported here, offers exciting possibilities for future development of successful antiobesity and antidiabetic therapies. RESEARCH DESIGN AND M...

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Previous experiments showed that ginsenoside Rb1 (GRb1) reduced infarct and neuronal deficit in rats followed by transient cerebral ischemia. The mechanism of this neuroprotective function is unclear. Here, we tested whether the effect of GRb1 can be achieved through preventing ischemic neuronal death, modulating apoptotic-related genes and affecting glial-derived neurotrophic factor (GDNF) exp...

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ژورنال

عنوان ژورنال: Diabetes

سال: 2010

ISSN: 0012-1797,1939-327X

DOI: 10.2337/db10-0315